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Lirica 50mg Capsule is used in adults to treat:
- Peripheral and central neuropathic pain
- Epilepsy (fits or seizures) in combination with other medicines
- Generalized Anxiety Disorder
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✅ Description:
Pregabalin is a medication used to treat various conditions, including neuropathic pain, fibromyalgia, postherpetic neuralgia, certain types of anxiety disorders, and epilepsy. It works by reducing the release of certain chemicals in the brain that transmit pain signals.
When taking pregabalin in oral forms like capsules or capsules, you can take it with or without food, but it's best to take it at the same time each day for optimal results. The dosage and duration of treatment will be determined by your doctor based on your condition and response to the medication. It's essential not to exceed the prescribed dose and to avoid discontinuing the medication abruptly, as it may lead to withdrawal symptoms such as headaches, mood swings, and irritability.
Pregabalin injections are administered by qualified healthcare professionals in clinical or hospital settings.
Pregabalin should not be used if you are allergic to it. Inform your doctor if you have kidney or heart problems. It is not recommended for use in children under 18 years old due to a lack of established safety and efficacy data. If you are pregnant or breastfeeding, consult your doctor before taking pregabalin.
Safety Advices
Alcohol
UNSAFE
It is advisable to avoid alcohol consumption while taking Lirica 50mg capsule as it may worsen dizziness.
Pregnancy
CONSULT YOUR DOCTOR
Lirica 50mg Capsule is generally not recommended for use in pregnant women unless considered necessary by a physician. Women of childbearing age should use non-hormonal contraceptive methods to prevent pregnancy during therapy with Lirica 50mg Capsule.
Breastfeeding
CONSULT YOUR DOCTOR
Lirica 50mg Capsule is not recommended for use in breastfeeding women unless considered necessary by a physician.
Driving
CAUTION
Avoid driving or operating heavy machinery if you experience dizziness or sleepiness after taking a Lirica 50mg Capsule.
Kidney
CAUTION
Use Lirica 50mg Capsule with caution in patients with kidney diseases, particularly those with decreased urination. Consult your doctor before taking it.
Liver
CAUTION
Exercise caution when using Lirica 50mg Capsule in patients with severe liver diseases. Consult your doctor before taking it.
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✔️ Uses of Lirica 50mg Capsule
- Diabetic Neuropathy
- Postherpetic Neuralgia
- Epilepsy
- Fibromyalgia
- Neuropathic pain
- Generalized anxiety disorder
✔️ How does Lirica 50mg Capsule work?
Pregabalin acts by reducing the action of certain chemical substances in the brain. Thus, it impairs the transmission of pain signals from the brain and relieves pain.
✔️ Side Effects of Lirica 50mg Capsule
Common side effects of pregabalin include dry mouth, swelling in the arms or feet, weight gain, weakness, confusion, and fatigue. If these side effects persist or worsen, it's important to consult your doctor. Pregabalin may also cause drowsiness or dizziness.
✔️ Quick Suggestions:
- Pregabalin should be taken as per the dose and duration prescribed by your doctor.
- It may cause blurring or loss of vision. Inform your doctor immediately if you notice any vision changes.
- Inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression, or suicidal thoughts or behavior.
- Do not stop taking the medication suddenly without talking to your doctor as it may worsen your underlying condition.
✔️ Indication of Lirica 50mg Capsules
- Pregabalin is prescribed for the treatment of neuropathic pain caused by diabetic peripheral neuropathy.
- It is used to treat post-herpetic neuralgia.
- Adult patients with partial-onset seizures may benefit from adjunctive therapy with pregabalin.
- Fibromyalgia is treated with pregabalin.
- Neuropathic pain occurring after a spinal cord injury is also managed with pregabalin.
✔️ Pharmacology
- Pregabalin, a structural derivative of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA), binds to the alpha-2-delta site in the central nervous system.
- It does not directly bind to GABAA, GABAB, or benzodiazepine receptors.
- Pregabalin has a high affinity for the alpha-2-delta site and shows 90% oral bioavailability.
- The medication is predominantly excreted unchanged by the kidneys, with a half-life of 6.3 hours in individuals with normal renal function.
✔️ Dosage & Administration of Lirica 50mg Capsule
- Dosage varies based on the condition being treated and individual patient response.
- For neuropathic pain associated with diabetic peripheral neuropathy, the maximum recommended dose is 100 mg three times a day.
- For post-herpetic neuralgia, the recommended dose ranges from 75 to 150 mg two times a day or 50 to 100 mg three times a day.
- Adjunctive therapy for partial-onset seizures typically starts at 150 mg per day and may be increased to a maximum of 600 mg/day.
- Fibromyalgia treatment involves a daily dose of 300 to 450 mg.
- Pregabalin pills can be taken at any time of day.
✔️ Interaction
- Pregabalin has no significant interactions with other antiepileptic medications or oral contraceptives.
- However, the effects of ethanol and lorazepam may be enhanced by pregabalin.
✔️ Contraindications
Patients with a known hypersensitivity to pregabalin or any of its components should avoid its use.
✔️ Pregnancy & Lactation
- Pregabalin is classified as pregnancy category C and should be used during pregnancy only if the potential benefits outweigh the risks.
- It can pass into breast milk, so its use in nursing mothers should be carefully considered.
✔️ Precautions & Warnings
- Pregabalin withdrawal without tapering may cause symptoms such as insomnia, nausea, headaches, and diarrhea.
- Creatinine kinase levels may increase with pregabalin use, and if myopathy is suspected, the medication should be stopped immediately.
✔️ Storage Conditions:
Store pregabalin away from light and moisture in a cool, dry place below 30°C, and keep it out of reach of children.
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here information is for informational purposes only.
The information contained herein should NOT be used as a substitute
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everything about particular health conditions,
lab tests, medicines, all possible side effects, drug interactions,
warnings, alerts, etc. Please consult your healthcare professional
and discuss all your queries related to any disease or medicine. We
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