Lirica 50mg Capsule 10pcs

Uses of Lirica 50mg Capsule

• Diabetic Neuropathy
• Postherpetic Neuralgia
• Epilepsy
• Fibromyalgia
• Neuropathic pain
• Generalized anxiety disorder

How does Lirica 50mg Capsule work?

Pregabalin acts by reducing the action of certain chemical substances in the brain. Thus, it impairs the transmission of pain signals from the brain and relieves pain.

Side Effects of Lirica 50mg Capsule

Common side effects of pregabalin include dry mouth, swelling in the arms or feet, weight gain, weakness, confusion, and fatigue. If these side effects persist or worsen, it's important to consult your doctor. Pregabalin may also cause drowsiness or dizziness.

Quick Suggestions:

• Pregabalin should be taken as per the dose and duration prescribed by your doctor.
• It may cause blurring or loss of vision. Inform your doctor immediately if you notice any vision changes.
• Inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression, or suicidal thoughts or behavior.
• Do not stop taking the medication suddenly without talking to your doctor as it may worsen your underlying condition.

Indication of Lirica 50mg Capsules

• Pregabalin is prescribed for the treatment of neuropathic pain caused by diabetic peripheral neuropathy.
• It is used to treat post-herpetic neuralgia.
• Adult patients with partial-onset seizures may benefit from adjunctive therapy with pregabalin.
• Fibromyalgia is treated with pregabalin.
• Neuropathic pain occurring after a spinal cord injury is also managed with pregabalin.

Pharmacology

• Pregabalin, a structural derivative of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA), binds to the alpha-2-delta site in the central nervous system.
• It does not directly bind to GABAA, GABAB, or benzodiazepine receptors.
• Pregabalin has a high affinity for the alpha-2-delta site and shows 90% oral bioavailability.
• The medication is predominantly excreted unchanged by the kidneys, with a half-life of 6.3 hours in individuals with normal renal function.

Dosage & Administration of Lirica 50mg Capsule

• Dosage varies based on the condition being treated and individual patient response.
• For neuropathic pain associated with diabetic peripheral neuropathy, the maximum recommended dose is 100 mg three times a day.
• For post-herpetic neuralgia, the recommended dose ranges from 75 to 150 mg two times a day or 50 to 100 mg three times a day.
• Adjunctive therapy for partial-onset seizures typically starts at 150 mg per day and may be increased to a maximum of 600 mg/day.
• Fibromyalgia treatment involves a daily dose of 300 to 450 mg.
• Pregabalin pills can be taken at any time of day.

Interaction

• Pregabalin has no significant interactions with other antiepileptic medications or oral contraceptives.
• However, the effects of ethanol and lorazepam may be enhanced by pregabalin.

Contraindications

Patients with a known hypersensitivity to pregabalin or any of its components should avoid its use.

Pregnancy & Lactation

• Pregabalin is classified as pregnancy category C and should be used during pregnancy only if the potential benefits outweigh the risks.
• It can pass into breast milk, so its use in nursing mothers should be carefully considered.

Precautions & Warnings

• Pregabalin withdrawal without tapering may cause symptoms such as insomnia, nausea, headaches, and diarrhea.
• Creatinine kinase levels may increase with pregabalin use, and if myopathy is suspected, the medication should be stopped immediately.

Storage Conditions:

Store pregabalin away from light and moisture in a cool, dry place below 30°C, and keep it out of reach of children.